Rat Lens Aldose Reductase inhibitory of Taraxacum mongolicum and two Cirsium species
نویسندگان
چکیده
منابع مشابه
Aldose reductase in early streptozotocin-induced diabetic rat lens.
The present study investigates the status of lens aldose reductase in the early streptozotocin-induced diabetic rat. Aldose reductase protein concentration, protein synthesis, and enzyme activity was assayed at 3 days and 14 days post-streptozotocin injection. Our results indicated that there was no significant difference between normal (control) and diabetic rat lenses in these parameters duri...
متن کاملActivators and inhibitors of lens aldose reductase.
Aldose reductase in a highly purified state is unstable. It requires the presence of thiol groups to maintain it in an active form. The enzyme apparently exists in 3 forms, only one of which is active. Tetramethylene glutaric acid (TMG) is an effective aldose reductase inhibitor. However, a relatively high level of TMG is needed to depress dulcitol synthesis in the lens incubated in a galactose...
متن کاملIsolation and Properties of Lens Aldose Reductase.
Exposure of the lens of the eye to a high concentration of an aldose, such as n-glucose, n-galactose, or n-xylose, results in the accumulation of the corresponding sugar alcohols. The high concentration which t.hese alcohols reach within the lens fibers appears to be responsible for t,he loss of clarity of the lens that is observed in experimental sugar cataracts (1). The reduced triphosphopyri...
متن کاملinhibitory activity of flavonoids on the lens aldose reductase of healthy and diabetic rats
aldose reductase is a critical enzyme in the polyol pathway that plays an important role in diabetes mellitus. inhibition of the activity of this enzyme can prevent cataract in diabetic patients’lenses. in this study the inhibitory effect of two flavonoids, quercetin and naringin, in the activity of aldose reductase in streptozotocin-induced diabetic and healthy rats were investigated. thirty m...
متن کاملDandelion (Taraxacum officinale and T mongolicum)
Common Names The English name dandelion is a corruption of the French dent de leon, meaning “lion’s tooth.” The herb is similarly named in many Indo-European tongues, also being called “lion’s tooth” in German (Löwenzahn) and Spanish (diente de leon). The name refers to the toothed margins of the leaves. In both modern French and English, the name for dandelion reflects its diuretic nature—bein...
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ژورنال
عنوان ژورنال: Journal of Applied Biological Chemistry
سال: 2008
ISSN: 1976-0442
DOI: 10.3839/jabc.2008.047